Role of exosome therapy in hair restoration
Hair loss caused by non-scarring alopecia, such as androgenetic alopecia (AGA) or alopecia areata (AA), is a major source of sickness and psychological hardship for individuals of all ages. There is a need for novel and creative medicines that provide long-term hair regeneration with minimal negative effects.
Exosomes are tiny (30–150 nm) cargo-delivering EVs that facilitate intercellular communication. They have a phospholipid bilayer and cargos that impact cell signalling and gene expression (e.g., cytokines, growth hormones, and regulatory microRNAs [miRNAs]). Although the specific method of action is unknown, it is thought that exosomes might promote crosstalk between epithelial and mesenchymal cells during the hair development cycle by modulating paracrine signalling. Exosomes generated from dermal papilla cells (DPCs; DPC-Exos), for example, have been demonstrated to upregulate the Wnt/-catenin pathway in outer root sheath cells (ORSCs), culminating in the telogen-to-anagen transition in mice.
Because of their regenerative and immunomodulatory capabilities, adipose-derived mesenchymal stem cell (ADMSC) exosomes have emerged as a viable therapy option for hair loss. Several studies have shown that ADMSC exosomes may enhance hair development by interfering with numerous cellular and molecular mechanisms in hair follicle biology.
Exosomes and other growth factors are injected into your scalp by Dr. Lakshmi Sowjanya, and these beneficial cells signal your hair follicles to rebuild and regrow hair. There is no need for surgery, and most patients handle therapy well.
What else? Exosomal hair restoration not only stimulates new hair development, but it also results in thicker hair, according to clinical research. Exosomal hair restoration may be the solution you’ve been looking for if you’re self-conscious about thinning hair.
Technologies based on exosomes
ADMSC exosomes may enhance hair growth via the following mechanisms:
- Hair follicle stem cell activation
- Angiogenesis Enhancement
- Immune response modulation
- Growth factors and signalling chemicals are delivered.
EXOHAIR Method
Exosomes are isolated from human mesenchymal stem cells, and their quality and quantity are rigorously assessed. Our exosome bank, which contains important lipids, messenger RNA, cytokines, and proteins, will be provided.
Are exomes safe?
Yes! Avni Aesthetics employs exosomes obtained from cutting-edge medical labs in accordance with the FDA and the Transplantation of Human Organs Act. Furthermore, all samples are checked with FDA-approved techniques. During your session, we will gladly give you additional, specific information.
One of the nicest aspects of exosomal hair regeneration is that there is no downtime. You can resume your usual activities, including bathing, immediately.
Mild soreness, redness, or swelling may occur at the injection site in some people. This normally resolves fast, and you can use over-the-counter drugs like paracetamol to help manage any discomfort.
You may witness fresh natural hair growth as soon as two to three months following your exosomal hair restoration therapy. You should expect new hair growth to continue for a year after your treatment, with the most obvious effects coming six months later.
Dr. Laxmi Sowjanya usually has patients return three to six months after their previous treatment to check on their progress and evaluate if an extra session of exosomal injections is necessary, depending on hair growth.
She may also offer other therapies based on your objectives and requirements, such as:
- Injections of platelet-rich plasma (PRP)
- Low-intensity laser treatment
- NeoGraft®-assisted ProGrowth Combination hair transplantation FUE Prescription-strength drugs that are custom-blended
Are you interested in learning more about exosomal hair restoration or another hair restoration treatment? Make an appointment with Dr. Lakshmi Sowjanya at Avni Aesthetics Clinic in Hyderabad over the phone at +91 9339234567.